With reference to T-lymphocytes (T-cells), consider the following statements:
1. T-cells mature in the bone marrow before circulating in the blood.
2. Helper T-cells play a crucial role in activating other immune cells.
3. Cytotoxic T-cells directly destroy virus-infected cells.

Which of the above statements is/are correct?
(a) 1 and 2 only
(b) 2 and 3 only
(c) 1 and 3 only
(d) 1, 2 and 3

Question

With reference to T-lymphocytes (T-cells), consider the following statements:
1. T-cells mature in the bone marrow before circulating in the blood.
2. Helper T-cells play a crucial role in activating other immune cells.
3. Cytotoxic T-cells directly destroy virus-infected cells.

Which of the above statements is/are correct?
(a) 1 and 2 only
(b) 2 and 3 only
(c) 1 and 3 only
(d) 1, 2 and 3

ONLiNE UPSC · Accepted Answer

Statement 1 is not correct: T-cells originate in the bone marrow but mature in the thymus, not in the bone marrow.

Statement 2 is correct: Helper T-cells (CD4) activate other immune cells like B-cells and macrophages.
Statement 3 is correct: Cytotoxic T-cells (CD8) directly kill virus-infected and cancerous cells.

Immunology

T-lymphocytes (T-cells)

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M Question 1	⏱ 0
With reference to T-lymphocytes (T-cells), consider the following statements: 1. T-cells mature in the bone marrow before circulating in the blood. 2. Helper T-cells play a crucial role in activating other immune cells. 3. Cytotoxic T-cells directly destroy virus-infected cells. Which of the above statements is/are correct? (a) 1 and 2 only (b) 2 and 3 only (c) 1 and 3 only (d) 1, 2 and 3